| The use of sub-2 µm particles is becoming increasingly popular
for applications in either High Throughput (HTS) assays or in Ultra High
Pressure Liquid Chromatography (U-HPLC). Sub-2 µm particle packed
columns offer advantages over the more traditional columns packed with
3 and 5 µm particles through shorter analysis times, improvements in
resolving power, sensitivity and peak capacity. When transferring methods
from HPLC to U-HPLC, several approaches can be taken, depending on the
analytical needs.
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